Square allows the player to chain multiple attacks at once. The player can manually assign any attack (punch, kick, etc.) they wish to Triangle, Square, and X buttons. Four dodge moves are mapped to the directions on the right analog stick. Using this button allows the player, as Gene, to jump up ladders, pick up items, and use special attacks that can only be used when the enemy is in a dazed or in a tired state. The player must manually turn around using a button, and all actions outside of basic attacks are performed via a context sensitive button.

God Hand is a 3D action game in which the player moves in all directions, attacking with the face buttons and using special moves. With most of her family killed by the demons, Olivia meets and joins Gene on his journey. Although he often appears outspoken and macho, he has a keen sense of justice and is accompanied by 19-year old Olivia, a descendant of a clan who protects one of the God Hand and fled. The game's protagonist is Gene, a 23-year old fighter who has one of the God Hands, that sought after by a group of demons.

A clan of humans was established to protect the God Hands that said that anyone who possesses them will be 'capable of becoming either god or demon.' The man was then given the title of 'God Hand' by the people he saved. A man holding the power of God within his arms defeated Angra, sending him into exile once again. Long ago, a fallen angel became the Demon King Angra and tried to destroy the world of humans using an army of demons and spectres.

The god hand game vector